{"id":18334,"date":"2023-04-07T15:26:28","date_gmt":"2023-04-07T19:26:28","guid":{"rendered":"https:\/\/www.myface.org\/?page_id=18334"},"modified":"2024-08-27T15:29:48","modified_gmt":"2024-08-27T19:29:48","slug":"vanderwoude","status":"publish","type":"page","link":"https:\/\/www.myface.org\/es\/craniofacial-conditions\/vanderwoude\/","title":{"rendered":"Van der Woude Syndrome"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"container\"><div class=\"sd-centered-wrapper\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"ult-spacer spacer-69ea54096f5d9\" data-id=\"69ea54096f5d9\" data-height=\"80\" data-height-mobile=\"50\" data-height-tab=\"\" data-height-tab-portrait=\"\" data-height-mobile-landscape=\"\" style=\"clear:both;display:block;\"><\/div><div id=\"ultimate-heading-719269ea54096f60e\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-719269ea54096f60e uvc-2838 \" data-hspacer=\"no_spacer\"  data-halign=\"center\" style=\"text-align:center\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-719269ea54096f60e h2'  data-responsive-json-new='{\"font-size\":\"desktop:46px;tablet:46px;tablet_portrait:46px;mobile_landscape:35px;mobile:35px;\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;color:rgba(255,255,255,0.68);\">Van der Woude Syndrome<\/h2><\/div><\/div><div class=\"ult-spacer spacer-69ea54096f627\" data-id=\"69ea54096f627\" data-height=\"80\" data-height-mobile=\"50\" data-height-tab=\"\" data-height-tab-portrait=\"\" data-height-mobile-landscape=\"\" style=\"clear:both;display:block;\"><\/div><\/div><\/div><\/div><\/div><\/div><\/div><!-- Row Backgrounds --><div class=\"upb_color\" data-bg-override=\"0\" data-bg-color=\"#2fbdd0\" data-fadeout=\"\" data-fadeout-percentage=\"30\" data-parallax-content=\"\" data-parallax-content-sense=\"30\" data-row-effect-mobile-disable=\"true\" data-img-parallax-mobile-disable=\"true\" data-rtl=\"false\"  data-custom-vc-row=\"\"  data-vc=\"8.0\"  data-is_old_vc=\"\"  data-theme-support=\"enable\"   data-overlay=\"false\" data-overlay-color=\"\" data-overlay-pattern=\"\" data-overlay-pattern-opacity=\"\" data-overlay-pattern-size=\"\"    ><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-10 vc_col-lg-offset-1\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p><strong><a href=\"\/craniofacial-conditions\/\">Craniofacial Conditions<\/a> &gt; Van der Woude Syndrome<br \/>\n<\/strong><\/p>\n\n\t\t<\/div>\n\t<\/div>\n<div class=\"ult-spacer spacer-69ea54096f831\" data-id=\"69ea54096f831\" data-height=\"15\" data-height-mobile=\"0\" data-height-tab=\"15\" data-height-tab-portrait=\"15\" data-height-mobile-landscape=\"15\" style=\"clear:both;display:block;\"><\/div><\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12 vc_col-lg-offset-3 vc_col-lg-6 vc_col-md-offset-3 vc_col-md-6 vc_col-xs-offset-1 vc_col-xs-10\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<div class=\"trp_language_switcher_shortcode\">\n<div class=\"trp-language-switcher trp-language-switcher-container\" data-no-translation >\n    <div class=\"trp-ls-shortcode-current-language\">\n        <a href=\"#\" class=\"trp-ls-shortcode-disabled-language trp-ls-disabled-language\" title=\"Espa\u00f1ol\" onclick=\"event.preventDefault()\">\n\t\t\t<img loading=\"lazy\" decoding=\"async\" class=\"trp-flag-image\" src=\"https:\/\/www.myface.org\/wp-content\/plugins\/translatepress-multilingual\/assets\/images\/flags\/es_ES.png\" width=\"18\" height=\"12\" alt=\"es_ES\" title=\"Espa\u00f1ol\"> Espa\u00f1ol\t\t<\/a>\n    <\/div>\n    <div class=\"trp-ls-shortcode-language\">\n                <a href=\"#\" class=\"trp-ls-shortcode-disabled-language trp-ls-disabled-language\"  title=\"Espa\u00f1ol\" onclick=\"event.preventDefault()\">\n\t\t\t<img loading=\"lazy\" decoding=\"async\" class=\"trp-flag-image\" src=\"https:\/\/www.myface.org\/wp-content\/plugins\/translatepress-multilingual\/assets\/images\/flags\/es_ES.png\" width=\"18\" height=\"12\" alt=\"es_ES\" title=\"Espa\u00f1ol\"> Espa\u00f1ol\t\t<\/a>\n                    <a href=\"https:\/\/www.myface.org\/es\/wp-json\/wp\/v2\/pages\/18334#TRPLINKPROCESSED\" title=\"English\">\n            <img loading=\"lazy\" decoding=\"async\" class=\"trp-flag-image\" src=\"https:\/\/www.myface.org\/wp-content\/plugins\/translatepress-multilingual\/assets\/images\/flags\/en_US.png\" width=\"18\" height=\"12\" alt=\"en_US\" title=\"English\"> English        <\/a>\n\n        <\/div>\n    <script type=\"application\/javascript\">\n        \/\/ need to have the same with set from JS on both divs. Otherwise it can push stuff around in HTML\n        var trp_ls_shortcodes = document.querySelectorAll('.trp_language_switcher_shortcode .trp-language-switcher');\n        if ( trp_ls_shortcodes.length > 0) {\n            \/\/ get the last language switcher added\n            var trp_el = trp_ls_shortcodes[trp_ls_shortcodes.length - 1];\n\n            var trp_shortcode_language_item = trp_el.querySelector( '.trp-ls-shortcode-language' )\n            \/\/ set width\n            var trp_ls_shortcode_width                                               = trp_shortcode_language_item.offsetWidth + 16;\n            trp_shortcode_language_item.style.width                                  = trp_ls_shortcode_width + 'px';\n            trp_el.querySelector( '.trp-ls-shortcode-current-language' ).style.width = trp_ls_shortcode_width + 'px';\n\n            \/\/ We're putting this on display: none after we have its width.\n            trp_shortcode_language_item.style.display = 'none';\n        }\n    <\/script>\n<\/div>\n<\/div>\n<h2>What is Van der Woude Syndrome?<\/h2>\n<p><span style=\"font-weight: 400;\">Van der Woude Syndrome is a rare genetic disorder characterized by a combination of physical and developmental anomalies. Van der Woude is caused by mutations in the IRF6 gene on chromosome 1, which plays a role in craniofacial development. It is primarily known for its distinctive facial features and can affect various organ systems.\u00a0<\/span><\/p>\n<h4><span style=\"font-weight: 900;\">Key features of Van der Woude Syndrome include:<\/span><\/h4>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Cleft Lip and\/or Palate:<\/b><span style=\"font-weight: 400;\"> A congenital split in the upper lip and\/or roof of the mouth, which can impact feeding and speech.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Facial Anomalies:<\/b><span style=\"font-weight: 400;\"> Characteristic facial features, including a broad forehead, flat midface, and sometimes a prominent nasal bridge.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Dental Anomalies:<\/b><span style=\"font-weight: 400;\"> Abnormalities in tooth development, such as missing or malformed teeth.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Developmental Delays:<\/b><span style=\"font-weight: 400;\"> Potential delays in physical and cognitive development.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">A confirmed diagnosis of Van der Woude Syndrome typically involves identifying these key features and may require genetic testing.<\/span><\/p>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12 vc_col-lg-offset-3 vc_col-lg-6 vc_col-md-offset-3 vc_col-md-6 vc_col-xs-offset-1 vc_col-xs-10 vc_col-has-fill\"><div class=\"vc_column-inner vc_custom_1708640251224\"><div class=\"wpb_wrapper\"><div class=\"vc_row wpb_row vc_inner vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-6\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"ult-spacer spacer-69ea54096fe00\" data-id=\"69ea54096fe00\" data-height=\"40\" data-height-mobile=\"0\" data-height-tab=\"40\" data-height-tab-portrait=\"40\" data-height-mobile-landscape=\"40\" style=\"clear:both;display:block;\"><\/div>\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<h3><b>Van der Woude Syndrome<\/b><\/h3>\n<p><b>Overview:<\/b><span style=\"font-weight: 400;\"> Van der Woude Syndrome is a rare genetic disorder associated with cleft lip and\/or palate and distinctive facial anomalies. The condition may affect various aspects of physical and developmental health.<\/span><\/p>\n<p><b>Prevalence:<\/b><span style=\"font-weight: 400;\"> Van der Woude Syndrome is extremely rare, with an estimated prevalence of less than 1 in 100,000 births.<\/span><\/p>\n<p><b>Causes:<\/b><span style=\"font-weight: 400;\"> The condition is usually caused by mutations in the IRF6 gene, which plays a role in craniofacial development.<\/span><\/p>\n<p><b>Diagnosis:<\/b><span style=\"font-weight: 400;\"> Diagnosis is based on clinical evaluation of physical features and may be confirmed through genetic testing for IRF6 mutations.<\/span><\/p>\n<p><b>Common Features:<\/b><span style=\"font-weight: 400;\"> Cleft lip and\/or palate, distinctive facial features, dental anomalies, and potential developmental delays.<\/span><\/p>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><div class=\"wpb_column vc_column_container vc_col-sm-6 vc_col-has-fill\"><div class=\"vc_column-inner vc_custom_1708640151407\"><div class=\"wpb_wrapper\">\n\t<div  class=\"wpb_single_image wpb_content_element vc_align_center wpb_content_element\">\n\t\t\n\t\t<figure class=\"wpb_wrapper vc_figure\">\n\t\t\t<div class=\"vc_single_image-wrapper   vc_box_border_grey\"><img loading=\"lazy\" decoding=\"async\" width=\"746\" height=\"486\" src=\"https:\/\/www.myface.org\/wp-content\/uploads\/2024\/08\/Screen-Shot-2024-08-27-at-2.25.37-PM.png\" class=\"vc_single_image-img attachment-large\" alt=\"\" title=\"Screen Shot 2024-08-27 at 2.25.37 PM\" srcset=\"https:\/\/www.myface.org\/wp-content\/uploads\/2024\/08\/Screen-Shot-2024-08-27-at-2.25.37-PM.png 746w, https:\/\/www.myface.org\/wp-content\/uploads\/2024\/08\/Screen-Shot-2024-08-27-at-2.25.37-PM-300x195.png 300w, https:\/\/www.myface.org\/wp-content\/uploads\/2024\/08\/Screen-Shot-2024-08-27-at-2.25.37-PM-18x12.png 18w\" sizes=\"auto, (max-width: 746px) 100vw, 746px\" \/><\/div>\n\t\t<\/figure>\n\t<\/div>\n\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p><span class=\"capt\">Cleft lip and cleft palate in an infant with van der Woude syndrome. (Photo courtesy of Mary J. Hauk, DDS.)<\/span><\/p>\n<div class=\"galleryLink\"><\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12 vc_col-lg-offset-3 vc_col-lg-6 vc_col-md-offset-3 vc_col-md-6 vc_col-xs-offset-1 vc_col-xs-10\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div>\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<h3><span style=\"font-weight: 800;\">Additional Characteristics of Van der Woude Syndrome<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">In addition to the core features, individuals with Van der Woude Syndrome may exhibit:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Facial Features:<\/b><span style=\"font-weight: 400;\"> Distinctive appearance, including a broad forehead, flat midface, and prominent nasal bridge.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Cleft Lip\/Palate:<\/b><span style=\"font-weight: 400;\"> Can affect feeding, speech, and require surgical intervention.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Dental Issues:<\/b><span style=\"font-weight: 400;\"> Missing or malformed teeth that may need orthodontic care.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Developmental Delays:<\/b><span style=\"font-weight: 400;\"> Variability in physical and cognitive development, requiring early intervention.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The range and severity of symptoms can vary greatly among individuals, making each case of Van der Woude Syndrome unique.<\/span><\/p>\n<h3><span style=\"font-weight: 800;\">Causes of Van der Woude Syndrome<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Van der Woude Syndrome is primarily caused by mutations in the IRF6 gene, which is crucial for the development of facial structures. These mutations are typically inherited in an autosomal dominant pattern. Genetic testing can confirm the presence of IRF6 mutations and aid in diagnosis.<\/span><\/p>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12 vc_col-lg-offset-3 vc_col-lg-6 vc_col-md-offset-3 vc_col-md-6 vc_col-xs-offset-1 vc_col-xs-10\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"vc_row wpb_row vc_inner vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<h3 style=\"text-align: center;\">myFace is pleased to offer these resources to help families and parents navigate the everyday issues.<\/h3>\n<\/div>\n<\/div>\n<div class=\" ubtn-ctn-center \"><\/div>\n\n\t\t<\/div>\n\t<\/div>\n<div class=\" ubtn-ctn-center \"><a class=\"ubtn-link ult-adjust-bottom-margin ubtn-center ubtn-large \" href=\"\/parent-guides\/\" ><button type=\"button\" id=\"ubtn-5133\"  class=\"ubtn ult-adjust-bottom-margin ult-responsive ubtn-large ubtn-no-hover-bg  none  ubtn-center   tooltip-69ea5409707ae\"  data-hover=\"\" data-border-color=\"\" data-bg=\"#d8007e\" data-hover-bg=\"\" data-border-hover=\"\" data-shadow-hover=\"\" data-shadow-click=\"none\" data-shadow=\"\" data-shd-shadow=\"\"  data-ultimate-target='#ubtn-5133'  data-responsive-json-new='{\"font-size\":\"desktop:18px;\",\"line-height\":\"\"}'  style=\"font-weight:normal;border:none;background: #d8007e;color: #ffffff;\"><span class=\"ubtn-hover\" style=\"background-color:\"><\/span><span class=\"ubtn-data ubtn-text \" >Learn More with our Parent Guides<\/span><\/button><\/a><\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<h3><span style=\"font-weight: 800;\">Diagnosis and Management<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Diagnosing Van der Woude Syndrome involves a comprehensive evaluation, including physical examination, imaging studies, and genetic testing. A multidisciplinary team of specialists is often required to address various medical, developmental, and educational needs.<\/span><\/p>\n<h4><span style=\"font-weight: 900;\">Medical Management<\/span><\/h4>\n<p><span style=\"font-weight: 400;\">Treatment may involve surgeries to correct cleft lip and\/or palate, along with ongoing care from dental and craniofacial specialists. Regular follow-ups are essential to monitor and address any associated health issues.<\/span><\/p>\n<h4><span style=\"font-weight: 900;\">Developmental Support<\/span><span style=\"font-weight: 900;\">\u00a0<\/span><\/h4>\n<p><span style=\"font-weight: 400;\">Early intervention with physical therapy, occupational therapy, and speech therapy can significantly improve outcomes for children with Van der Woude Syndrome.<\/span><\/p>\n<h4><span style=\"font-weight: 900;\">Family Support<\/span><\/h4>\n<p><span style=\"font-weight: 400;\">Counseling and support groups offer invaluable resources for families, providing emotional support and practical advice. Connecting with organizations dedicated to Van der Woude Syndrome can be beneficial.<\/span><\/p>\n<p><a href=\"https:\/\/www.myface.org\/online-groups\/\"><b>Learn more about myFace\u2019s Support Group Options<\/b><\/a><\/p>\n<h3><span style=\"font-weight: 800;\">Treatment for Van der Woude Syndrome<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Treatment for Van der Woude Syndrome is tailored to each individual\u2019s needs, focusing on managing specific symptoms and challenges. This typically includes surgical interventions for cleft lip and\/or palate, ongoing specialist care, and developmental therapies to support growth and learning. Educational support and family counseling are also crucial for providing comprehensive care and guidance.<\/span><\/p>\n<h3><span style=\"font-weight: 800;\">Living with Van der Woude Syndrome<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Despite the challenges associated with Van der Woude Syndrome, many individuals lead fulfilling lives with appropriate support and interventions. Early diagnosis and a proactive approach to medical care, education, and social integration are key to optimizing quality of life.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For nearly 70 years, myFace has worked with patients and families to provide comprehensive care and support. In addition to offering state-of-the-art medical care, myFace provides emotional support groups, workshops, and educational webinars that offer guidance, counsel, and resources for patients, families, and the broader craniofacial community.<\/span><\/p>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><!-- Row Backgrounds --><div class=\"upb_color\" data-bg-override=\"0\" data-bg-color=\"\" data-fadeout=\"\" data-fadeout-percentage=\"30\" data-parallax-content=\"\" data-parallax-content-sense=\"30\" data-row-effect-mobile-disable=\"true\" data-img-parallax-mobile-disable=\"true\" data-rtl=\"false\"  data-custom-vc-row=\"\"  data-vc=\"8.0\"  data-is_old_vc=\"\"  data-theme-support=\"enable\"   data-overlay=\"false\" data-overlay-color=\"\" data-overlay-pattern=\"\" data-overlay-pattern-opacity=\"\" data-overlay-pattern-size=\"\"    ><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p><a class=\"sd-more sd-all-trans\" href=\"https:\/\/www.myface.org\/es\/craniofacial-conditions\/vanderwoude\/#more-18334\">Leer m\u00e1s<\/a><\/p>","protected":false},"author":21,"featured_media":0,"parent":11228,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"full-width-page.php","meta":{"footnotes":""},"class_list":["post-18334","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Van der Woude Syndrome | myFace<\/title>\n<meta name=\"description\" content=\"Van der Woude Syndrome is a rare genetic disorder characterized by cleft lip\/palate &amp; distinctive facial features. 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